Colleen Bailey1,2, Ross Williams2, Gord Lueck2, Mostafa Atri3, Peter N. Burns1,2, Greg J. Stanisz1,2, Georg A. Bjarnason4
1Medical Biophysics, University of Toronto, Toronto, ON, Canada; 2Imaging Research, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; 3Medical Imaging, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; 4Medical Oncology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Patients with renal cell carcinoma were treated with the drug Sunitinib and examined by DCE-MRI and contrast-enhanced ultrasound. DCE-MRI provided the volume transfer constant, Ktrans, and the extravascular extracellular volume fraction ve. Disruption-replenishment provided the relative blood volume change. Combining the information from both imaging techniques provides a fuller picture of the tumour response to treatment.