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Abstract #0480

Clinical Validation of Multi-Contrast Delayed Enhancement (MCDE) for Wall Motion and Viability Imaging

Jay Stephen Detsky1,2, Kim A. Connelly1,3, Gideon A. Paul1,4, John J. Graham3, Alexander J. Dick4, Graham A. Wright1,2

1Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; 2Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; 3Cardiology, St. Michael's Hospital, Toronto, Ontario, Canada; 4Schulich Heart Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada


The clinical accuracy and reproducibility of a new multi-contrast delayed enhancement (MCDE) sequence was tested in 41 patients. MCDE can be used to simultaneously visualize cardiac wall motion and viability; MCDE showed excellent agreement with the conventional wall motion and delayed enhancement sequences in this study. MCDE provides improved visualization of small infarcts and halves the number of breath-holds required wall motion and viability imaging.