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Abstract #0481

Papillary Muscle Infarction by Delayed-Enhancement Magnetic Resonance Imaging: Reproducibility and Potential as an Independent Predictor of Ischemic Mitral Regurgitation

Thananya Boonyasirinant1, Ronan Curtin2, Randolph M. Setser1, Michael L. Lieber3, Scott D. Flamm1

1Radiology, Cleveland Clinic, Cleveland, OH, USA; 2Cardiology, Cleveland Clinic, Cleveland, OH, USA; 3Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA


Delayed-enhancement MRI (DE-MRI) has been accepted as the high resolution, non-invasive infarction specific imaging for evaluation of myocardial viability. However the prevalence, feasibility, and reproducibility of papillary muscle infarction identification and the relationship between IMR severity and papillary muscle viability have not been established. This study demonstrated the feasibility of papillary muscle infarction identification using DE-MRI with excellent intra-observer and inter-observer reproducibility. The presence of posterior papillary muscle infarction and impaired EF are independent predictors of MR severity in ICM patients. The identification of papillary muscle infarction may provide novel insights into improved surgical strategies for IMR.