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Abstract #0702

Myocardial Perfusion MRI Using SW-CG-HYPR in Canines with Improved Spatial Coverage, Resolution and SNR

Lan Ge1, Aya Kino1, Daniel Lee1, Rohan Dharmakumar1, Mark Griswold2, Charles Mistretta3, James Carr1, Debiao Li1

1Northwestern University, Chicago, IL, USA; 2Western Reserve University, OH, USA; 3University of Wisconsin-Madison, WI, USA

The diagnostic value of myocardial perfusion MRI is limited by the low spatial coverage, resolution, SNR, and cardiac motion related image artifacts. This work compared SW-CG-HYPR method with conventional clinical protocols for myocardial perfusion and demonstrated the feasibility of SW-CG-HYPR method for detecting the myocardial territory supplied by a stenotic coronary artery using a controlled animal model. Using this method, the acquisition time per slice was reduced by a factor of 4, which should substantially reduce cardiac motion artifacts; the number of slices was doubled; the spatial resolution was improved by a factor of 2 and the SNR by >50% as compared to conventional methods.