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Abstract #0703

First Pass Contrast Enhanced MRI Shows Disparate Manifestations in Exercise-Induced Perfusion Improvement in Non-Transmural Infracted and Remote Myocardium

Mao-Yuan Marine Su1, B-C Lee2, Y-W Wu2, H-Y Yu3, W-C Chu4, W-Y I. Tseng5

1Institute of Biomedical Engineering, National Yang-Ming University, Taipei, Taiwan; 2Internal Medicine, National Taiwan University Hospital; 3Surgery, Natioanl Taiwan University Hospital; 4Institute of Biomedical Engineering, Natioanl Yang-Ming University; 5Center for Optoelectronic Biomedicine, National Taiwan University College of Medicine, Taipei, Taiwan

Previous studies have demonstrated that exercise training can improve myocardial perfusion for patients with myocardial infarction (MI).However, the effect of exercise training on the non-transmural infarct myocardium and residual viable myocardium still remains unclear. Using MRI, our results suggest that the effects of exercise training on the non-transmural infarct and non-infarct remote zone might be different. In the remote zone, improvement of MPR after exercise training is mainly due to reduced coronary vascular resistance. For the residual viable myocardium in the non-transmural infarct zone, the observed increased stress perfusion might be attributed to exercise-induced angiogenesis.