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Abstract #0925

Single Cell Tracking of Neural Progenitors Labeled in Vivo with Micron Sized Particles of Iron Oxide (MPIO) Into Specific Layers of the Olfactory Bulb

James P. Sumner1, Stephen Dodd1, Elizabeth Wayne1,2, Der-Yow Chen1, Yun Chen1,3, Dragan Maric1,4, Alan P. Koretsky1

1National Institutes of Health, Bethesda, MD, USA; 2University of Pennsylvania, Philadelphia, PA, USA; 3National Institute of Standards and Technology; 4NINDS FACS Facility, Bethesda, MD, USA

In this work, MRI was used to track neural progenitors (NPCs) into the olfactory bulb with 50 μm isotropic resolution. At this resolution and with the aid of manganese, NPCs were identified and quantified in each layer of the bulb. Olfactory bulbs from naive and animals exposed to amyl acetate were compared.