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Abstract #0928

In Vivo Differentiation of Magnetically Labeled Mesenchymal Stem Cells Into Hepatocytes for Cell Therapy to Repair Damaged Liver

Shenghong Ju1, Gao-jun Teng1, Haihua Lu1

1Department of Radiology, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China

The aims of this study are to build a new in vivo model named as Iron-GFP/CCl4 model for monitoring the transdifferentiation of magnetically labeled GFP-positive MSCs into albumin-positive hepatocytes under the specific niche made by CCl4 induced persistent liver damage, and to track labeled MSCs by MR imaging in vivo in mice.