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Abstract #0956

Grey/white Matter Contrast in Phase Images: Is It Susceptibility or Is It Not?

Jos Pedro Marques1, Rolf Gruetter1

1Centre d'Imagerie BioMdicale, Ecole Polytechnique Fdrale de Lausanne, Lausanne, Vaud, Switzerland

The tissue phase variations between grey and white matter are thought to originate from either tissue susceptibility variations or variations of macromolecule content affecting the water chemical shift. In this abstract we test these two hypotheses by trying to fit a high resolution fieldmap with the expected spatial distribution calculated after segmentation of a high resolution T1 weighted image. Results tentatively suggest the dominance of a non-susceptibility origin.