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Abstract #0977

Imaging of Brain Metastases of Bronchial Carcinoma with 7 Tesla MRI

Christoph Moenninghoff1,2, Stefan Maderwald1,2, Philipp Schuett3, Jens M. Theysohn1,2, Oliver Kraff1,2, Mark E. Ladd1,2, Thomas Gauler3, Michael Forsting1,2, Isabel Wanke1,2

1Erwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Essen, NRW, Germany; 2Department for diagnostic and interventional radiology and neuroradiology, University Hospital Essen, Essen, NRW, Germany; 3Department of Internal Medicine, Cancer Research, University Hospital Essen, Essen, NRW, Germany

The purpose of this work was to compare the depiction of brain metastases of bronchial carcinomas with susceptibility-weighted and contrast-enhanced MRI at 7T and 1.5T. Twelve patients underwent MR examinations with SWI and contrast-enhanced T1-weighted MPRAGE sequences at both field strengths using a higher spatial resolution at 7T. 7T SWI MIPs depicted 20 more microhemorrhages in 12 patients compared to 1.5T. Double-dose contrast-enhanced 7T versus 1.5T T1-weighted images depicted the same number of metastases in 6 patients, whereas single-dose enhanced 7T T1w sequences missed several micrometastases. Application of double-dose CA and the higher achievable spatial resolution and sensitivity for susceptibility artifacts of 7T MRI are beneficial for the depiction of brain metastases.