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Abstract #1008

1H MRSI Detection of Elevated Total Creatine in Brain Cancer: A Cautionary Tale

Dikoma C. Shungu1, Xiangling Mao2, Apostolos J. Tsiouris1, Carl E. Johnson1, Jonathan P. Dyke1, Linda A. Heier1, Joseph O. Comunale1, John A. Boockvar3, Susan C. Pannullo3

1Radiology, Weill Cornell Medical College, New York, NY, USA; 2Radiology, Weill Cornell Medical College , New York, NY, USA; 3Neurological Surgery, Weill Cornell Medical College, New York, NY, USA

This study reports on the observation of clear and dramatic elevations of total creatine (tCr) by 1H MRSI in three patients with brain tumors, which suggests caution in using ratios relative to tCr to express the levels of other 1H MRS metabolites currently a common practice.