Abstract #1309

Diffusion Tensor Imaging of Subjects with Cervical Spondlytic Myelopathy: Use of the Eigenvalues as Indicators of Spinal Stenosis

Enedino Hernandez^1,2, Alex L. Mackay^3,4, Erin L. MacMillan⁵, Burkard Mdler⁶, David K. Li², M F. Dvorak⁷, Teodoro Cordova⁸, Alonso Ramirez-Manzanares⁹, C Laule²

¹Instituto de Fisica, Universidad de Guanajuato, Leon, Guanajuato, Mexico; ²Dept. of Radiology, University of British Columbia, Vancouver, British Columbia, Canada; ³Dept. of Radiology, University of British Columbia, Vancouver, British Columbia, Canada; ⁴Dept. of Physics & Astronomy, University of British Columbia, Vancouver, British Columbia, Canada; ⁵Dept. of Clinical Research, University of Bern, Bern, Switzerland; ⁶Philips Healthcare, Vancouver, British Columbia, Canada; ⁷International Collaboration on Repair Discoveries, Vancouver, British Columbia, Canada; ⁸Fisica Medica y Materiales Biologicos, Instituto de Fisica, Universidad de Guanajuato, Leon, Guanajuato, Mexico; ⁹8Facultad de Matematicas, Universidad de Guanajuato, Guanajuato, Mexico

In this work the results of a study investigating Cervical Spondylotic Myelopathy subjects using DTI are presented. We analyzed the FA as well as the parallel (LP) and radial (LR) eigenvalues of the diffusion tensor in stenotic and normal appearing regions of the cord. Diffusion Tensor eigenvalues were approximately constant along the spine, but with variations in regions with stenosis. FA was generally higher in the stenotic regions; however, LP and LR were generally reduced in regions of stenosis.