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Abstract #1310

Optimization of Flip Angles in SPGR Imaging for Quantitative T1 Mapping of the Cervical Spinal Cord at 3.0 T

Iordanis E. Evangelou1, Vasiliki N. Ikonomidou1, Marcela Montequin2, Nancy D. Richert1, Henry F. McFarland1, Steve Jacobson1

1Neuroimmunology Branch, NINDS, NIH, Bethesda, MD, USA; 2Functional MRI Facility, NIMH, NIH, Bethesda, MD, USA

T1 maps can be calculated from SPGR images acquired with different flip angles and/or repetition times. Here we optimize flip angles for accurate T1 measurement of the cervical spinal cord at 3.0T under the presence of noise in a Monte Carlo simulation using the Driven Equilibrium Single Pulse Observation of T1 (DESPOT1) sequence.