Abstract #1371

Preliminary Experiences with Implementing High Resolution CSF-Suppressed Optic Nerve DTI at 3.0T with and Without Parallel Imaging

Rebecca Sara Samson¹, Mark R. Symms², David L. Thomas³, Madhan Kolappan¹, David H. Miller¹, Claudia A M Wheeler-Kingshott¹

¹Department of Neuroinflammation, UCL Institute of Neurology, London, UK; ²Department of Clinical & Experimental Epilepsy, UCL Institute of Neurology, London, UK; ³Medical Physics & Bioengineering, UCL, London, UK

There are several technical challenges associated with studying the optic nerve (ON) using DTI, in particular its small size, motion, contamination of signal by fat and Cerebrospinal Fluid (CSF), and susceptibility effects pose significant problems. We present our preliminary experiences with the implementation of ON DTI on two different manufacturers 3.0T scanners using different data acquisition methods both with and without the use of parallel imaging.