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Abstract #1375

Apparent Diffusion Coefficient Measurement of in Vivo Atherosclerotic Plaque Obtained from Six Human Subjects Using 2D Ss IMIV DWEPI Technique on 3T System

Seong-Eun Kim1, Eun-Kee Jeong1, J. Rock Hadley1, John A. Roberts1, Gernald A. Trieman2,3, Laura C. Bell1, Dennis L. Parker1

1UCAIR Department of Radiology, University of Utah, Salt Lake City, UT, USA; 2Surgical Service, VA Salt Lake City Health Care System; 3Department of Surgery School of Medicine, University of Utah

In this work we present the in vivo ADC measurement of in vivo atherosclerotic plaque obtained from six human subjects. The results obtained indicate that ADC map may be of substantial value as a new contrast for carotid plaque imaging. Although our ADC values obtained using the 2D ss IMIV DWEPI technique fall within the range of previously reported ADC value in an ex-vivo study, there is no previously known ADC value of each plaque component from an in-vivo study. The technique demonstrated here can now be used to further investigate the ADC in all types of plaque components.