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Abstract #1378

Feasibility of In-Vivo Diffusion Tensor Echo Planar Imaging and Fiber Tracking at 14.1T

Nicolas Kunz1,2, Yohan van de Looij1,2, Petra S. Hppi2, Stphane V. Sizonenko2, Rolf Gruetter1,3

1Laboratory for Functional and Metabolic Imaging, Ecole Polytechnique Fdrale de Lausanne, Lausanne, Switzerland; 2Division of Child Growth & Development, Department of Pediatrics, University of Geneva, Geneva, Switzerland; 3Department of Radiology, University of Geneva and Lausanne, Geneva and Lausanne, Switzerland

Despite the high interest of combination of DTI and MRS at ultra-high magnetic field, none such multimodal in vivo studies in the rodent brain have been published. This combination is very challenging due to different requirements of the two modalities. High resolution MRS requires the use of a transceive surface coil. The aim of this study was to implement a DTI-EPI sequence with whole brain coverage at 14.1T, while using a surface coil as both transmitter and receiver. We demonstrate the feasibility of in vivo DTI-EPI at 14.1T using a transceive surface coil with whole brain coverage.