Exploring the White Matter Microstructure Underpinning Electrophysiological Dynamics: A Combined DT-MRI and MEG Study

Derek K . Jones¹, Alex Leemans¹, Christopher John Evans¹, Krish D. Singh¹, Suresh D. Muthukumaraswamy¹

Neuronal oscillations at specific frequencies appear to be fundamental to the implementation of perception and cognition within the brain. Gamma oscillations (30-100 Hz) have been proposed as a temporal coding scheme through which distributed neuronal groups are able to synchronise allowing communication between these areas and underlying the binding of stimulus features. We combined DT-MRI and MEG data on gamma oscillations to address the question of whether whether there is a role for white matter pathways in gamma oscillatory behaviour. Certain aspects of our finds are expected, while others are not leading to important insights about analysis of DT-MRI data.