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Abstract #1412

Quantitative Mapping of Diffusion Characteristics Under the Cortical Surface

Bang-Bon Koo1, Vibhu Sachdev1, Jong Min Lee2, Dae-Shik Kim1

1Biomedical imaging center, Boston University, Boston, MA, USA; 2Biomedical Engineering, Hanyang University, Seoul, Korea

We introduced a new method that allows robust localized analysis of WM diffusivity in peripheral cortex and showed that DTI mapping of peripheral WM structure reveals regional characteristics. While we applied this framework on young normal population, we need to confirm whether peripheral diffusion successfully reveal spatio-temporal age related maturation process. Moreover, combining functional imaging techniques will allow to investigate structure-functional relationships.