Segmentation and Characterisation of White Matter Tracts in Late Childhood and Adolescence

Jonathan D. Clayden¹, Catherine J. Riney¹, Janine Cooper¹, Monica Muoz¹, Chris A. Clark¹

This work describes the application of the recently-developed probabilistic neighbourhood tractography (PNT) method to data acquired from subjects in late childhood or adolescence. Using this method, we segmented a number of white matter tracts in each subject's data, and investigated the effects of age and gender on diffusion parameters. We found clear differences between the tracts, and we demonstrate some evidence for a lateralisation effect which is at least partly modulated by gender.