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Abstract #1456

Stability of Diffusion Direction Based Thalamus Segmentation

Sarah C. Mang1, Uwe Klose1, Susanne Reiterer1,2, Wolfgang Grodd1

1Section Exp. MRI of CNS, Diagnostic and Interventional Neuroradiology, Tbingen, Germany; 2Hertie Institute for Clinical Brain Research, General Neurology, University of Tbingen, Tbingen, Germany

A simple diffusion direction based segmentation method was used to distinguish thalamic sub-structures on 53 healthy volunteers. This segmentation method classifies voxels according to the orientation of their principal diffusion direction. The results of this simple segmentation method were stable in the evaluated subject population. Our segmented clusters did in addition show a correspondence to the clusters segmented with a more complicated connectivity based segmentation approach.