Abstract #1457

Detection of Motor Thalamus by Probabilistic Diffusion Density : Verification by Motor BOLD-Based FMRI

Tzu-chen Yeh¹, Zong-Kai Hsu², Sue-Jin Lin², Chou-Ming Cheng¹, Jen-Chuen Hsieh², Low-Tone Ho¹

¹Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan, Taiwan; ²Institute of Brain Science, National Yang-Ming University, Taipei, Taiwan, Taiwan

Structural MRI and functional MR data with motor task of right index were obtained from fourteen normal subjects. Thalamal parcellation by probabilistic diffusion density tractography (PDD) was performed with two protocols. Protocol I applied the Brodmann areas 1-6 as targets in normalized space. And protocol II used the central correlates of motor fMRI as target. Two similarity indices of thalamus parcellation were calculated as SI(BA1-6) = 0.56and SI(motor-fMRI) = 0.96 regarding to protocol I and II, respectively. We concluded the PDD-based parcellation of motor thalamus can be validated by using the fMRI of a simple motor task.