Johnny Ng1, CheukYing Tang1,2, Emily Eaves1, Isabella Kanellopoulou2, Xinsu Mai1, David Carpenter1, David Schroeder3, Roberto Colom4, Richard J. Haire3,5
1Radiology, Mount Sinai School of Medicine, New York, NY, USA; 2Psychiatry, Mount Sinai School of Medicine, New York, NY, USA; 3Johnson O'Connor Research Foundation, Chicago, IL, USA; 4Universidad Autónoma de Madrid (UAM), Spain; 5School of Medicine, UC Irvine, Irvine, CA, USA
We studied correlations between regional white matter integrity, using DTI with a Siemens 3T Allegra, and intelligence factor scores with gender effect in 40 control subjects. Fractional anisotropy (FA) and directional color maps were computed using in-house software. Region of Interests were defined on color-coded maps. FA values were extracted and merged with intelligence factor scores for correlation analysis. Significant positive and negative correlations were detected. These findings were consistent with a recent report on DTI/IQ correlations on subjects 5-18 where correlations were negative in males and positive in females as they aged. Our results confirmed these findings into adulthood.
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