Meeting Banner
Abstract #1475

Dynamic Contrast Enhanced Whole Brain Perfusion Using a Rapid 3D T1-Weighted Sequence at 7T

Paul S. Morgan1,2, Emma C. Tallantyre3, Ali Al-Radaidah3, Jennifer E. Dixon4, Matthew J. Brookes4, Nikos Evangelou3, Peter G. Morris4

1Radiology & Radiological Sciences, Medical University of South Carolina, Charleston, SC, USA; 2Academic Radiology, University of Nottingham, Nottingham, UK; 3Clinical Neurology, University of Nottingham, Nottingham, UK; 4Sir Peter Mansfield MR Centre, University of Nottingham, Nottingham, UK

7T has shown potential in imaging the human brain. We investigated the feasibility of acquiring whole brain perfusion data during administration of a bolus of gadolinium-based contrast agent at 7T using a 3D T1-weighted technique previously demonstrated at lower field. Successful data were acquired on three patients with multiple sclerosis, yielding perfusion values for white and gray matter in the range obtained by other perfusion studies, indicating that this technique may be performed successfully at 7T.