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Abstract #1494

In Vivo Diffusion Tensor Magnetic Resonance Imaging and Fiber Tracking of the Mouse Brain

Laura-Adela Harsan1, Dominik Paul1, Susanne Schnell1, Bjorn W. Kreher1, Juergen Hennig1, Jochen F. Staiger2, Dominik von Elverfeldt1

1Department of Diagnostic Radiology, University Hospital Freiburg, Medical Physics, Freiburg, Germany; 2Department of Neuroanatomy, Institute for Anatomy and Cell Biology, Center for Neuroscience, Freiburg, Germany

In vivo DT-MRI and fiber tracking was used in the present study to describe major white matter fiber tracts of the mouse brain and also to identify for the first time non-invasively the rich connectivity between the amygdala and different brain regions. Beside the standard fiber tracking procedure we generated probability maps of connectivity with which it was possible to investigate in a statistical sense - all possible connecting pathways between two seed points. We show here applications to determine the connection probability between regions belonging to the visual or limbic systems.