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Abstract #1526

Double Acquisition Background Suppressed (DABS) FAIR at 3T and 7T: Advantages for Simultaneous BOLD and CBF Acquisition.

Roman Wesolowski1, Penny A. Gowland1, Susan T. Francis1

1School of Physics and Astronomy, University of Nottingham, Sir Peter Mansfield Magnetic Resonance Centre, Nottingham, Nottinghamshire, UK

We have developed and optimised a Double Acquisition Background Suppression (DABS) method for simultaneous CBF and BOLD image collection using FAIR at 3 and 7T. Background suppression reduces physiological noise in ASL by acquiring images close to the null point, but this prohibits simultaneous BOLD acquisition. DABS is a new method which acquires a second BOLD weighted acquisition at the end of each TR period. We have used this technique to obtain qualitative maps of CBF and BOLD haemodynamic responses to a finger tapping task at both 3 and 7T. This technique improves the detection of CBF changes whilst retaining good BOLD contrast.