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Abstract #1527

Background Suppression in Multi Slice Arterial Spin Labeling

Wouter M. Teeuwisse1,2, Maarten J. Versluis1,2, Mark A. van Buchem1,2, Matthias J.P. van Osch1,2

1Radiology, Leiden University Medical Center, Leiden, Netherlands; 2C.J.Gorter Center for High Field MRI, Leiden, Netherlands

In Arterial Spin Labeling, background suppression (BS) is known to enable a two fold increase in SNR of the perfusion images. However, for multi slice acquisition BS is only optimal for the first slice and will deteriorate in later slices due to regrowth of the background signal. In this study, efficiency of BS and its relation to SNR is investigated and also, whether addition of BS inversion pulses that are played between acquisition of slices improves BS and SNR for later slices.