Single Pair Arterial Spin Labeling Imaging

Jiabao He¹, Andrew M. Blamire¹

Arterial spin labelling is a valuable MR technique to examine cerebral blood flow. Due to the small amplitude of contrast, a large number of acquisitions have to be collected, resulting in prolonged experimental duration. Two major sources of signal loss are T1 relaxation of tagged magnetization during transit between the labelling zone and imaging slice and T2* relaxation during imaging readout. In this work, we present a FAIR based technique to accelerate perfusion image acquisition through a combination of single slice imaging with a tightly restricted inversion slab to reduce transit region and spiral readout to mininize TE.