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Abstract #1563

Modulating Brain Activity Via Multi-Echo FMRI Neurofeedback

Mark Chiew1,2, Audrey Yu Ching Kuo2,3, Simon J. Graham1,2

1Rotman Research Institute, Toronto, ON, Canada; 2Medical Biophysics, University of Toronto, Toronto, ON, Canada; 3Sunnybrook Health Sciences Centre, Toronto, ON, Canada

The use of functional MRI (fMRI) to perform neurofeedback (NF) experiments is of increasing interest. Here a novel multi-echo pulse sequence designed for real-time fMRI and NF is validated by explicit demonstration of NF using the right and left primary sensorimotor cortices (SMC). Participants viewed a colour bar that quantified SMC laterality and were asked to modulate their brain activity to match the target laterality by performing a unilateral hand clenching task. In 18 experiments over 4 participants, there was 100% success in matching the target task condition.