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Abstract #1618

Susceptibility Artefacts in Experiments Involving Changes in Inspired Oxygen Level

Nicholas Paul Blockley1, Ian D. Driver2, Susan T. Francis2, Joseph A. Fisher3, Penny A. Gowland2

1SPMMRC, School of Physics and Astronomy, University of Nottingham, Nottingham, UK; 2SPMMRC, School of Physics and Astronomy,, University of Nottingham, Nottingham, UK; 3University of Toronto, Toronto, Ontario, Canada

Changes in oxygen concentration in the nasal cavity during a hyperoxic challenge cause a variation in the susceptibility gradient at the sinus-tissue interface. We found that this caused a measurable dipolar pattern of signal change in slices inferior to the corpus callosum along with more subtle changes in superior slices. This artefact will be