Abstract #1742

Validation of Cine-FLASH as a Method to Image Late Gd Enhancement in Mice

Andrea Protti¹, Alexander Alexander Sirker², Tobias Schaeffter³, Ajay Shah², Rene Botnar³

¹Cardiovascular Division and Division of Imaging Sciences, Kings College London BHF Centre of Excellence, London, UK, UK; ²Cardiovascular Division, Kings College London BHF Centre of Excellence, London, UK; ³Division of Imaging Sciences, Kings College London BHF Centre of Excellence, London, UK

Late Gadolinium Enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging is usually performed by a T1-weighted sequence with an inversion recovery (IR) pre-pulse. Although the images achieve good contrast from areas of Gd agent uptake, there are several drawbacks such as absence of contrast between Gd infarcted areas and blood; image blurring due to ECG and respiration instability; anatomical information lost. In order to avoid such limitations, a cine-FLASH is suggested as a more reliable method of imaging LGE in mice 2 days after MI.