Abstract #1744

Intra-Individual Comparison of 0.1 Mmol/kg Versus 0.2 Mmol/kg Gadobutrol for Magnetic Resonance Late Enhancement Imaging at 3 Tesla

Frank Grothues¹, Hagen Boenigk¹, Martin Kanowski², Joachim Graessner³, Katrin Christel Sprung³, Martin Rohrer⁴, Ruediger Christian Braun-Dullaeus¹

¹Cardiology, University Hospital Magdeburg, Magdeburg, Germany; ²Neurology, University Hospital, Magdeburg, Germany; ³Siemens Medical Solutions, Erlangen, Germany; ⁴Bayer Schering Pharma AG, Berlin, Germany

Two doses of gadobutrol (0.1 mmol/kg or 0.2 mmol/kg) were evaluated qualitatively and quantitatively for late enhancement (LE) imaging at 3T in an intra-individual comparison in 15 patients with a history of myocardial infarction. Qualitative judgement by blinded observers revealed an in tendency better image quality with fewer artifacts and less noise with the higher contrast dosage. Quantitative measurements of infarct size and contrast-to-noise ratio between infarcted and remote myocardium were significantly higher with the 0.2 mmol/kg dosage and should therefore be preferred.