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Abstract #1797

The Effects of Contrast Agent on Quantitative Morphological LV Parameters at 3T

Shona Matthew1, Richard Stephen Nicholas2, Stephen James Gandy3, Shelley Anne Waugh2, Elena Crowe4, Richard A. Lerski2, Malcolm H. Dunn1, J Graeme Houston4

1Physics and Astronomy, St Andrews University, St Andrews, Fife, UK; 2Medical Physics, Ninewells Hospital, Dundee, Tayside, UK; 3Medical Physics, Ninewells Hospital, Dundee, Fife, UK; 4Clinical Radiology, Ninewells Hospital, Dundee, Tayside, UK

This study addresses LV analysis at 3T in order to determine whether the administration of contrast agent has a significant effect on cardiac parameters. Pre and post contrast images of 12 healthy volunteers (no previous cardiac illness and Framingham score < 20%) were analysed. A paired t-test was performed on differences between mean pre and post contrast values of ejection fraction, end diastolic volume, end systolic volume, stroke volume, cardiac output and mass. Statistically significant differences were found for EDV, SV and mass which may impact on patient care. Findings also suggest normal ranges need to be established at 3T.