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Abstract #1961

Feasibility and Reproducibility of T1ρ MRI Examining Osteoarthritis in a Guinea Pig Model

Matthew Fenty1, Erin McArdle1, Victor Kassey1, Walter RT Witschey 2nd1,2, Arijitt Borthakur1, Ravinder Reddy

1Radiology, University of Pennsylvania, Philadelphia, Pa, USA; 2Graduate Group in Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, Pa, USA

Feasibility and reproducibility of T1p; MRI was assessed in spontaneously developing osteoarthritis in Dunkin Hartley guinea pigs. A high degree of precision of intra- and inter- animal T1p measurement and age-dependent increase in T1p values is demonstrated.