Abstract #1961

Feasibility and Reproducibility of T1ρ MRI Examining Osteoarthritis in a Guinea Pig Model

Matthew Fenty¹, Erin McArdle¹, Victor Kassey¹, Walter RT Witschey 2nd^1,2, Arijitt Borthakur¹, Ravinder Reddy

¹Radiology, University of Pennsylvania, Philadelphia, Pa, USA; ²Graduate Group in Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, Pa, USA

Feasibility and reproducibility of T1p; MRI was assessed in spontaneously developing osteoarthritis in Dunkin Hartley guinea pigs. A high degree of precision of intra- and inter- animal T1p measurement and age-dependent increase in T1p values is demonstrated.