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Abstract #2077

Improved Contrast Enhancement of Experimentally Induced Rat Hepatocellular Carcinoma Using New Blood Pool Contrast Agent Dendrimers DTPA-D1Glc(OH)

Yasuo Takehara1, Takashi Aoki2, Mitsuji Yamashita2, Michio Fujie3, Katsuaki Muramatsu3, Harumi Sakahara3, Norihiro Sadato4, Hiroyasu Takeda3

1Radiology, Hamamatsu University Hospital, Hamamatsu, Shizuoka, Japan; 2Shizuoka University Graduate School of Technology; 3Hamamatsu University School of Medicine; 4National Institute for Physiological Science

Newly developed blood pool agent can provide improved and sustained contrast enhancement of experimentally induced rat hypervascular hepatocellular carcinoma with lower dosage of 1/8 of Gd-DTPA at molecular basis.