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Abstract #2092

DCE-MRI Temporal Resolution Requirements for Vascular Permeability Measurements in Rhesus Macaque Reproductive Tissues

Ian J. Tagge1, Cecily V. Bishop2, Richard L. Stouffer2,3, Charles S. Springer, Jr. 1, Xin Li1

1Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR, USA; 2Division of Reproductive Sciences, ONPRC, Oregon Health & Science University, Portland, OR, USA; 3Department of Obstetrics and Gynecology, Oregon Health & Science University

The female reproductive uterus and ovary are among the few normal tissues to undergo periodic changes in angiogenesis. Using a primate model (rhesus macaque) we investigated the effects of temporal resolution on the precision and accuracy of Ktrans determination with the second-generation three-site water exchange DCE-MRI model.