Hoanglong Nguyen1, Ke Nie1, Jeon-Hor Chen1,2, Chieh-Chih Hsu2, Daniel Chang1, Sandy Shih2, Doris Hsu2, Byron Feig1, Dustin Newell1, Hon J. Yu1, Orhan Nalcioglu1, Min-Ying Lydia Su1
1Tu & Yuen Center for Functional Onco-Imaging, University of California, Irvine, CA, USA; 2Department of Radiology, China Medical University, Taiwan
We measured the breast volume, fibroglandular tissue volume, and the percent density in 321 women from 3 racial background (Caucasians, Hispanics, and Asians). The age and race-dependence of breast density was analyzed using logistic regression models controlling for multiple variables. The fibroglandular tissue volume and the percent density showed a strong age-dependence. The Asian women had higher percent density compared to the White and Hispanic women, but the differences were found to come from the smaller breast volume in the Asians containing comparable fibroglandular tissue volume. Our findings were consistent with results analyzed using mammography from a large subject cohort.