Ralf Berthold Loeffler1, Jane Hankins2, Ray Song1, Adam M. Winchell1, Mary Beth McCarville1, Claudia Maria Hillenbrand1
1Radiological Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA; 2Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA
Liver iron quantification with T2* measurements is gaining clinical acceptance. So far only breath-hold techniques are validated with liver biopsies. This study compared different free-breathing techniques (regular free breathing, navigated free breathing) with a breath-hold technique that was validated with liver biopsies. Liver T2* values were very similar for the free breathing techniques and for the breath-hold technique in 3 pediatric patients with moderate to strong hepatic iron overload.