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Abstract #2169

Comparison of Parallel Image Reconstruction Methods to Acquire High Resolution ADC-Tensor Images of 3He in Human Lungs.

Maxim V. Terekhov1, Julien Rivoire1, Florian M. Meise1, Davide Santoro1, Wolfgang G. Schreiber1

1Department of Radiology, Section of Medical Physics, Mainz University Medical School, Mainz, Germany

Measuring the Apparent Diffusion Coefficient (ADC) of hyperpolarized 3He-gas in lungs is a proven method of non-invasive probing the integrity of lungs microstructure. Due to sophisticated configuration of small airways the diffusion in lungs is anisotropic and can be characterized by ADC-tensor. The ADC-tensor symmetry may provide valuable additional information about the pathological changes of lung microstructure. The purpose of current work is to demonstrate the possibilities, which provides the phased-array parallel acquisition for improving the efficiency of 3He ADC-tensor measurements and to make comparison of different reconstruction methods of the parallel imaging datasets to improve quality of ADC-tensor maps.