Comparison of Parallel Image Reconstruction Methods to Acquire High Resolution ADC-Tensor Images of 3He in Human Lungs.

Maxim V. Terekhov¹, Julien Rivoire¹, Florian M. Meise¹, Davide Santoro¹, Wolfgang G. Schreiber¹

Measuring the Apparent Diffusion Coefficient (ADC) of hyperpolarized 3He-gas in lungs is a proven method of non-invasive probing the integrity of lungs microstructure. Due to sophisticated configuration of small airways the diffusion in lungs is anisotropic and can be characterized by ADC-tensor. The ADC-tensor symmetry may provide valuable additional information about the pathological changes of lung microstructure. The purpose of current work is to demonstrate the possibilities, which provides the phased-array parallel acquisition for improving the efficiency of 3He ADC-tensor measurements and to make comparison of different reconstruction methods of the parallel imaging datasets to improve quality of ADC-tensor maps.