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Abstract #2170

Effect of Echo Spacing on the T2 of Hyperpolarized He3 in the Healthy Human Lung at 1.5T

John P. Mugler, III1, G Wilson Miller1, Talissa A. Altes1, Jaime F. Mata1, Eduard E. de Lange1, W Al Tobias2, Gordon D. Cates, Jr. 1,2, James R. Brookeman1

1Radiology, University of Virginia, Charlottesville, VA, USA; 2Physics, University of Virginia, Charlottesville, VA, USA


The T2 value for He3 in the healthy human lung was measured at 1.5T using a CPMG spin-echo-train pulse sequence with echo spacings of 10, 20 and 30 ms. The mean T2 values from five subjects were 232, 182 and 160 ms for echo spacings of 10, 20 and 30 ms, respectively. There was a statistically significant decrease in the T2 value as the echo spacing increased from 10 to 20 ms, and a trend toward further decreases in T2 as the echo spacing increased from 20 to 30 ms.

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