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Abstract #2189

Free Breathing Hyperpolarized 3He Lung Ventilation Spiral MR Imaging. Implementation and Validation on a Clinical Scanner

Elise Bannier1, Bruno Neyran1, Katarzyna Cieslar1, Julien Rivoire1, Sophie Gaillard1, Abdulrazzaq Sulaiman1, Emmanuelle Canet-Soulas1, Yannick Crmillieux1

1Universit de Lyon, CREATIS LRMN, Lyon, France

The purpose of this study was to validate in vivo on rabbits a spiral free breathing imaging protocol developed on a clinical scanner. A model of MR signal dynamics was used upstream to optimize sequence and protocol parameters and downstream to extract global physiological parameters from the acquired signal. Time resolved images were reconstructed using cine retrospective synchronization and parametric maps computed.