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Abstract #2190

Hyperpolarized Helium-3 Ventilation and ADC MR Imaging in the Treatment of Patients with Inoperable Lung Cancer.

Jaime Mata1, Ke Sheng2, Jing Cai2, Paul Read2, Talissa Altes1, Eduard de Lange1, Klaus Hagspiel1, William Tobias3, Gordon Cates3, James Brookeman1, John Mugler III1

1Radiology, University of Virginia, Charlottesville, VA, USA; 2Radiation-Oncology, University of Virginia, Charlottesville, VA, USA; 3Physics, University of Virginia, Charlottesville, VA, USA


Non-small-cell carcinoma alters the regional anatomy and physiology of the lung. Our purpose was to investigate, using hyperpolarized (hp) He-3, the regional ventilatory and structural pulmonary changes in patients with inoperable lung carcinoma.