Abstract #2198

Reproducibility and Volume-Dependency of Regional Measurements of Lung Ventilation by Hyperpolarized 3He MRI

Kiarash Emami¹, Stephen Kadlecek¹, John MacDuffie-Woodburn¹, Jianliang Zhu², Stephen Pickup¹, Jiangsheng Yu¹, Matthew Stetz¹, Masaru Ishii³, Michael Stephen⁴, Rahim Rizi¹

¹Radiology, University of Pennsylvania, Philadelphia, PA, USA; ²Division of Thoracic Surgery, University of Pennsylvania, Philadelphia, PA, USA; ³Department of Otolaryngology – Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, USA; ⁴Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania, Philadelphia, PA, USA

This work assesses the reproducibility of measurements of lung ventilation and their dependency on the administered hyperpolarized 3He volume using a serial ventilation sequence.