High Spatial and Spectral Resolution (HiSS) MRI of the Prostate: A Pilot Study

Milica Medved¹, Aytekin Oto¹, Gregory S. Karczmar¹

Reliable navigation of prostate biopsy cores is necessary to improve accuracy. High spatial and spectral resolution (HiSS) imaging provides high-quality morphologic images and spectrally resolved water resonance in each voxel. Detailed shape of the water resonance is sensitive to perfusion, hypoxia, certain protein deposits, etc. and could in principle visualize cancerous tissue. We report HiSS MR imaging of human prostate in five healthy volunteers. Morphologic images derived from HiSS data show better fat suppression and higher anatomic detail, compared to clinical fast spin echo images. In healthy volunteers, there was no observable structure to the water resonance.