Matthias C. Roethke1, Matthias P. Lichy2, Alexander Pelzer3, Claus H. vonWeyhern4, David Schilling5, Claus D. Claussen6, Heinz P. Schlemmer7
1Dep. of Diagnostic Radiology, University Tuebingen, Tuebingen, Germany; 2Dep. of Diagnostic Radiology, University Tuebingen, Germany; 3Dep. of Urology, Tuebingen University, Germany; 4Dep. of Pathology, Tuebingen University, Germany; 5Dep. of Urology, Germany; 6Dep. of Diagnostic Radiology, Tuebingen University, Germany; 7Dep. of Diagnostic Radiology, Tuebingen University, Tuebingen, Germany
Multifocality of cancer was found in 90% of the patients on histopathologic whole mounted sections. DWI proved to be highly accurate in tumors larger than 5-10mm. Particularly DWI yielded no false positive findings and would therefore not increase the amount of negative MR-guided prostate biopsies. DWI including automatic calculation of ADC maps is fast and robust to perform and applicable within a MR guided biopsy procedure. The accuracy of DWI for tumor detection and its usability for MR-guided biopsy within one single examination could be further improved at 3.0T enabling higher spatial resolution and the application of higher b-values.
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