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Abstract #2251

Multiparametric 3T MR Imaging for Detection of Prostate Cancer with Surgical Correlation

Baris Turkbey1, Haresh Mani2, Marcelino Bernardo1, Yuxi Pang3, Kiranpreet Khurana4, Paul Albert5, Peter Pinto4, Maria Merino2, Peter L. Choyke1

1Molecular Imaging Program, NCI, NIH, Bethesda, MD, USA; 2Laboratory of Pathology, NCI, NIH, Bethesda, MD, USA; 3Philips Healthcare, Bethesda, MD, USA; 4Urologic Oncology Branch, NCI, NIH, Bethesda, MD, USA; 5Biometric Research Branch, Division of Cancer Treatment and Diagnosis, NCI, NIH, Bethesda, MD, USA

While 3T endorectal MRI of prostate reveals comparable sensitivity and specificity to those reported for 1.5T the combined use of multiparametric MRI (DCE-MRI and MR spectroscopy) improves the positive predictive value for tumor detection.