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Abstract #2341

Weighted Combination of Multichannel 1H-MRS Data: Comparison of SNR- And SVD-Based Methods by Simulated, in Vitro and in Vivo Data

Alexander Gussew1, Jacob Orme1,2, Reinhard Rzanny1, Jrgen R. Reichenbach1

1Medical Physics Group, IDIR, University Clinics of Jena, Jena, Thuringia, Germany; 2Brigham Young University, Provo, UT, USA

Using the phased array RF coils in MRS examinations can distinctly improve spectra quality because of their higher signal sensitivity compared to single channel circular polarized coils. However, exact estimation of channel weights is essential for the correct reconstruction of combined data. The accuracy of two different approaches for the weight extraction first based on channel SNR and second on multi channel data Singular Value Decomposition, were quantitatively compared using simulated as well as experimental in vitro and in vivo multi-channel data sets with two different SNR levels.