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Abstract #2359

Estimating Saturation Factors for PRESS with Inhomogeneous B1 at 7T

Douglas Kelley1, Esin Ozturk-Isik2, Janine Lupo2

1Applied Science Laboratory, GE Healthcare, San Francisco, CA, USA; 2Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA

B1 inhomogeneity and increasing T1 values in vivo at 7T produce unwanted signal variation in PRESS. Calculation of PRESS saturation factors due to B1 inhomogeneity at 7T allows for assessment of appropriate acquisition timing and, given knowledge of metabolite T1 relaxation times, correction of signal variation for uncoupled spins like NAA, choline and creatine.