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Abstract #2520

Proton Resonance Frequency Shift Weighted Imaging for the MR Monitoring of the Thermotherapy

Yi-Lu Tsai1, Jyun-Wen Chen1, Teng-Yi Huang1, Hsu-Hsia Peng2, Wen-Shiang Chen3, Wen-Yih Isaac Tseng4

1Dept. of Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan; 2Dept. of Electrical Engineering, National Taiwan University, Taipei, Taiwan; 33. Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei , Taiwan; 44. Center for Optoelectronic Biomedicine, Medical College of National Taiwan University, Taipei, Taiwan

Owing to the temperature dependence of most MRI parameters such as the T1 and the proton density, the magnitude images obtained by the PRF-based sequences also exhibit temperature-related image contrast. In this study, we aimed to further enhance the contrast by a post-processing method similar to the recently advanced susceptibility-weighted imaging (SWI) method. In MRI-guided focused ultrasound (MRIgFUS) applications, the frequency dispersion induced by the local temperature elevation has the spin behavior similar to that of the susceptibility-related frequency shift. For this reason, we proposed to apply a SWI-like post-processing method, PRFSWI, to reconstruct the PRF-shift contrast for MRIgFUS.