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Abstract #2521

Rapid FUS Focal Spot Localization Based on MR-ARFI.

Elena Kaye1,2, Jing Chen1,2, Kim Butts Pauly2

1Electrical Engineering, Stanford University, Palo Alto, CA, USA; 2Radiology, Stanford University, Palo Alto, CA, USA

For various therapeutic applications, focused ultrasound (FUS) is used in thermanl mode or mechanical mode. Mechanical mode has been used for temporary BBB disruption and for targeted drug delivery, but the monitoring of these treatments has been challenging since there no measurable temperature increase. This study investigates a single shot reduced FOV EPI for imaging tissue displacement induced by acoustic radiation force, ARFI, as a potential monitoring tool. The results of the study show that the focal spot of the mechanical mode FUS can be localized with the proposed technique, and that the measured displacement is comparable to the dispacement measured by previously proposed line scan technique.