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Abstract #2537

Real Time Volumetric Temperature Imaging of High Intensity Focused Ultrasound Thermal Ablation on the Liver

Bruno Quesson1, Christophe Laurent2, Gregory Maclair1, Charles Mougenot3, Baudouin denis de Senneville1, Mario Ries1, Chrit Moonen1

1UMR5231 CNRS/Universit Bordeaux 2, Laboratory for Molecular and Functional Imaging, Bordeaux, France; 2Hepatic Surgery, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France; 3Philips healthcare, Bordeaux, France

This study proposes a rapid and volumetric MR-thermometry during High Intensity Focused Ultrasound ablations performed in the liver of pigs. Several HIFU ablations were monitored in vivo with a multislice, motion compensated, single shot EPI sequence acquired at a 2.5Hz update rate/volume. Temperature standard deviation was about 1C. Area were the thermal dose calculated online reached the lethal value were confirmed by histology results on the liver (ablation) and skin (no alteration). This work demonstrates the possibility to precisely monitor HIFU ablations with high temporal and spatial resolutions in vivo on a mobile organ and in the surrounding tissues (skin).