Abstract #2538

Transcatheter Intraarterial Perfusion (TRIP)-MRI Monitoring of Radiofrequency Ablation in Rabbit VX2 Liver Tumors

Dingxin Wang¹, Kent Sato², Johnathan Chung², Richard Tang², Rachel Klein², Barbara Szolc-Kowalska³, Gayle Woloschak³, Reed Omary^1,4, Andrew Larson^1,4

¹Departments of Radiology and Biomedical Engineering, Northwestern University, Chicago, IL, USA; ²Department of Radiology, Northwestern University, Chicago, IL, USA; ³Radiation Oncology, Northwestern University, Chicago, IL, USA; ⁴Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA

4D TRIP-MRI offers the potential to objectively monitor serial changes in tumor perfusion during RFA therapies (rather than a single post-RFA confirmation measurement with current DCE approaches). Combined with current MR-thermometry approaches, TRIP-MRI may provide a useful tool for intra-procedural monitoring of coagulation zone formation by thermal ablation.