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Abstract #2538

Transcatheter Intraarterial Perfusion (TRIP)-MRI Monitoring of Radiofrequency Ablation in Rabbit VX2 Liver Tumors

Dingxin Wang1, Kent Sato2, Johnathan Chung2, Richard Tang2, Rachel Klein2, Barbara Szolc-Kowalska3, Gayle Woloschak3, Reed Omary1,4, Andrew Larson1,4

1Departments of Radiology and Biomedical Engineering, Northwestern University, Chicago, IL, USA; 2Department of Radiology, Northwestern University, Chicago, IL, USA; 3Radiation Oncology, Northwestern University, Chicago, IL, USA; 4Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA


4D TRIP-MRI offers the potential to objectively monitor serial changes in tumor perfusion during RFA therapies (rather than a single post-RFA confirmation measurement with current DCE approaches). Combined with current MR-thermometry approaches, TRIP-MRI may provide a useful tool for intra-procedural monitoring of coagulation zone formation by thermal ablation.